Antibiotische Verbindungen, genannt A/16686-Faktoren A'1,A'2 und A'3

Composés antibiotiques nommés A/16686 facteurs A'1, A'2 et A'3

Novel antibiotic compounds named A/16686 Factors A'1, A'2 and A'3

Abstract

The invention relates to depsipeptidic compounds related to antibiotic A/16696 complex of formula I Said compounds are named antibiotic A/16686 factors A'1, A'2 and A'3, respectively and are produced by fermentation of the microorganism Actinoplanes sp ATCC 33076 or a natural or artifical mutant thereof under appropriate conditions or by contacting antibiotic A/16686 factors A1, A2 and A3 or a mixture thereof with the mycelium of Actinoplanes sp ATCC 33076 or a natural or articial mutant thereof. The compounds have antibacterial activity, in particular, against widely diffused gram-positive bacteria and are particularly useful for topical treating of wound infections and acne.

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Patent Citations (1)

    Publication numberPublication dateAssigneeTitle
    EP-0046201-A2February 24, 1982Gruppo Lepetit S.P.A.Antibiotique A/16686 facteur A2, son procédé de préparation et l'antibiotique A/16686 facteurs A1 et A3 coproduits

NO-Patent Citations (1)

    Title
    JOURNAL OF ANTIBIOTICS, vol. XXXVII, no. 4, 1984, pages 309-317, Tokyo, JP; B. CAVALLERI et al.: "A-16686, a new antibiotic from Actinoplanes; I. Fermentation, isolation and preliminary physico-chemical characteristics"

Cited By (7)

    Publication numberPublication dateAssigneeTitle
    EP-0427142-A1May 15, 1991GRUPPO LEPETIT S.p.A.Verfahren zur Rückgewinnung von Antibiotikum A/16686
    EP-0976394-A1February 02, 2000Biosearch Italia S.p.A.New injectable formulations
    US-5539087-AJuly 23, 1996Gruppo Lepetit SpaAntibiotic A/16686 recovery process
    US-6720305-B1April 13, 2004Vicuron Pharmaceuticals Inc.Injectable formulations containing ramoplanin
    US-7169890-B2January 30, 2007Vicuron Pharmaceuticals Inc.Process for the production of ramoplanin-like amide derivatives
    WO-0006119-A1February 10, 2000Biosearch Italia S.P.A.Nouvelles formulations injectables contenant ramoplanine
    WO-03076460-A1September 18, 2003Vicuron Pharmaceuticals Inc.Procede destine a produire des derives d'amide de type ramoplanine